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Updated: Jan 6, 2026

Author Spotlight: Integrating BRET-Based Assays and Rare Mutation Analysis to Decipher RAF Kinase Regulation in Live Cells
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自己抑制および活性BRAF-MEK1-14-3-3複合体の構造

Eunyoung Park1,2, Shaun Rawson2, Kunhua Li1,2

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Nature
|October 4, 2019
PubMed
まとめ

構造的な洞察は,14-3-3タンパク質がBRAFキナーゼの活動をどのように調節するかを明らかにする. これらの発見は BRAF を説明します.

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