関連する実験動画

Updated: Jan 6, 2026

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels
16:36

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels

Published on: May 18, 2009

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完全長さのP2X7構造は,パルミトイレーションがチャンネル脱敏を防ぐ方法を示しています

Alanna E McCarthy1, Craig Yoshioka2, Steven E Mansoor1

  • 1Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA; Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR 97239, USA.

Cell
|October 8, 2019
PubMed
まとめ

P2X7受容体の構造的な洞察は,そのユニークな細胞質領域が無感化を防止し,核酸を結合させ,この重要なイオンチャネルの理解を進めることを明らかにします.

キーワード:
アポトーシスクリオ電子顕微鏡サイトプラズマ領域感受性の低下グアノシンヌクレオチドリガンドゲートイオンチャネルパルミトイレーション純素受容体 (P2X)構造生物学亜鉛イオン複合体

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