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Updated: Jan 6, 2026

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
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移転性DCは,TGF-βを活性化し,先行したCD8+ T細胞を組織内定の記憶運命に先導する

Vinidhra Mani1,2, Shannon K Bromley1,3, Tarmo Äijö4

  • 1Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA.

Science (New York, N.Y.)
|October 12, 2019
PubMed
まとめ

変形成長因子β (TGF-β) はリンパ節内のナイブT細胞を表遺伝的に条件付け,上皮の定住記憶T (eTRM) 細胞になるように準備します. このプロセスは免疫監視とワクチン開発に不可欠です.

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