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Updated: Jan 6, 2026

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
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Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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シェイサ7は,ベンゾジアゼピン作用を制御するGABAA受容体の補助サブユニットである

Wenyan Han1, Jun Li1, Kenneth A Pelkey2

  • 1Synapse and Neural Circuit Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

Science (New York, N.Y.)
|October 12, 2019
PubMed
まとめ

Shisa7タンパク質は,シナプスにおけるγ-アミノバター酸A型受容体 (GABAARs) を調節し,その機能に影響を与え,ベンゾジアゼピン効果を強める. その欠如はGABAergic伝達を阻害し,diazepamを減少させます.

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