C型肝炎
PubMedで要約を見る
まとめ
この要約は機械生成です。C型肝炎ウイルス (HCV) は世界中で何百万人に感染しており,診断と治療は限られており,撲滅の努力を妨げています. 診断と治療へのアクセスを拡大することは,WHOの2030年目標を達成するために不可欠です.
科学分野
- ヘパトロジー
- 感染症
- 公衆衛生
背景
- C型肝炎ウイルス (HCV) 感染は,約7100万人の慢性感染者がいる世界的な健康問題です.
- HCVの感染は主に皮膚経由の血液感染で発生し,薬物注射者,同性愛者,囚人などの高リスクグループがあります.
- 慢性的なHCV感染は20~30年以内に肝硬変,肝不全,肝細胞癌などの重篤な合併症を引き起こす可能性があります.
研究 の 目的
- C型肝炎ウイルスの感染が 世界的に蔓延していることを 強調するためです
- HCVの診断と治療のギャップを強調する
- HCVの排除のためのアクセシブルな診断とパンゲノタイプの直接作用抗ウイルス治療の重要性を強調する.
主な方法
- 世界的なHCV発生率と流行に関する疫学データ分析.
- 感染経路と高リスク集団の見直し
- HCVの現在の診断率と治療開始率の評価
主要な成果
- 2015年,世界のHCV感染率は10万人当たり23.7人であり,新規感染者は175万人でした.
- HCVのゲノタイプ1,3,4は,世界的に最も一般的です.
- C型肝炎を患っている人のうち 診断を認識している人は20%で 診断された人のうち 治療を受けている人はわずか15%です
結論
- 治療効果のある直接作用の抗ウイルス療法にもかかわらず,診断と治療に重大な障壁が残っています.
- 世界保健機関が定めた2030年のHCV撲滅の目標を達成するには より多くの診断と医療へのつながりが必要です
- HCVの根絶には,手頃な価格で診療所での診断とパンゲノタイプの直接作用抗ウイルス療法への普遍的なアクセスが不可欠です.
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