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Updated: Jan 5, 2026

Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation
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Constructing Thioether/Vinyl Sulfide-tethered Helical Peptides Via Photo-induced Thiol-ene/yne Hydrothiolation

Published on: August 1, 2018

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可視光促進C-Hアルキレーションによるヒスティジン特異ペプチド改変

Xiaoping Chen1, Farong Ye1, Xiaosheng Luo1

  • 1Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering , Shanghai Jiao Tong University , 800 Dongchuan Road , Shanghai 200240 , China.

Journal of the American Chemical Society
|October 23, 2019
PubMed
まとめ

ペプチドにおけるヒスティディンの化学選択的改変は,可視光促進C-Hアルキル化を使用して可能である. この新しいラジカル媒介法は,以前の技術の限界を克服し,ペプチドとタンパク質化学におけるより広範な応用を可能にします.

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