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Updated: Jan 5, 2026

Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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MHC-IIネオアンチゲンは,腫瘍の免疫性と免疫療法への反応を決定する

Elise Alspach1,2, Danielle M Lussier1,2, Alexander P Miceli1,2

  • 1Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.

Nature
|October 25, 2019
PubMed
まとめ

癌の免疫編集と免疫療法への反応の成功は,CD8+とCD4+T細胞の両方に依存する. 腫瘍細胞は,効果的な抗腫瘍免疫のために,CD4+T細胞活性化のためのMHCクラスII抗原を提示する必要があります.

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