工業化された微生物群の脆弱性
Justin L Sonnenburg1,2, Erica D Sonnenburg1
1Department of Microbiology and Immunology and Center for Human Microbiome Studies, Stanford University, Stanford, CA, USA. jsonnenburg@stanford.edu erica.sonnenburg@stanford.edu.
Science (New York, N.Y.)
|October 26, 2019
まとめ
現代の生活様式と 医療の介入により 人間の腸内微生物群が変化し 健康を害しています 科学者たちは 生態学的なアプローチを用いて これらの重要な微生物の生態系を研究し 保護することを提案しています
科学分野:
- 微生物学
- エコロジー
- 人間 の 健康
背景:
- 人間の体には 複雑な微生物の生態系があります 微生物群は健康に不可欠です
- 世界的なライフスタイルの変化や 抗生物質のような介入により 腸内微生物の構成が大きく変化しています
- これらの変化は,特に工業社会では,人間の健康に有害な微生物の機能の喪失につながる可能性があります.
研究 の 目的:
- ヒトの腸内微生物群に 現代の生活様式が与える影響を 強調するためです
- 人間の微生物群の研究と保存のための生態学的原理の適用を提案する.
- 微生物の健康に悪影響を及ぼす可能性があることを強調する.
主な方法:
- ヒトの微生物群の構成と機能に関する現在の理解のレビュー
- 微生物群の研究のためのマクロエコロジーと保全科学から抽出した類似性.
- 抗生物質と食事を含む微生物群の変化に影響を与える要因の議論
主要な成果:
- 腸内微生物群の重要な変化は,ライフスタイルの変化と医学的慣行により,世界的に観察されています.
- 微生物の多様性や機能の喪失は 健康状態の最適化に欠ける可能性がある.
- 現在の微生物群の変化は不可逆であり 長期的な健康リスクをもたらす可能性があります
結論:
- 人類の微生物群は 現代の環境や生活様式により 有害な変化を遂げています
- 生態学的なアプローチは,ヒトの微生物群を理解し,保護するための貴重な枠組みを提供します.
- 微生物生態系を人間の健康のために保護するには 積極的な研究と保全戦略が必要です
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