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Updated: Jan 3, 2026

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
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Published on: June 6, 2017

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TRF2のCDKリン酸化は,細胞サイクル中のtループの動態を制御する

Grzegorz Sarek1, Panagiotis Kotsantis1, Phil Ruis1

  • 1The Francis Crick Institute, London, UK.

Nature
|November 15, 2019
PubMed
まとめ

シェルテリン複合タンパク質TRF2は,テロメアTループのダイナミクスを調節するために,細胞サイクルフォスフォスイッチを使用します. このメカニズムは正確なテロメア複製を保証し,DNA損傷信号を防止し,染色体の末端を保護します.

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