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Updated: Jan 3, 2026

Assays for the Degradation of Misfolded Proteins in Cells
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ユビキチン-プロテアソームシステムによる細胞品質管理とオートファギー

Christian Pohl1,2, Ivan Dikic1,2,3

  • 1Institute of Biochemistry II, Faculty of Medicine, Goethe University, 60590 Frankfurt am Main, Germany. dikic@biochem2.uni-frankfurt.de pohl@em.uni-frankfurt.de.

Science (New York, N.Y.)
|November 16, 2019
PubMed
まとめ

細胞は品質管理のためにユビキチン-プロテアソームシステム (UPS) とオートファギーを使用し,損傷したタンパク質と臓器を分解します. これらのシステムは 細胞の恒常性を維持するために 生物物理的要因と区画化に基づいて 自己組織化します

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