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Updated: Jan 3, 2026

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NLRP3炎症ゾームの活性化がタウ病変を誘発する

Christina Ising1,2, Carmen Venegas1, Shuangshuang Zhang1,2

  • 1Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital of Bonn, Bonn, Germany.

Nature
|November 22, 2019
PubMed
まとめ

マイクログリア内のNLRP3炎症体は,アルツハイマー病の進行に不可欠です. この炎症ソームを阻害すると,タウ病理が減少し,アミロイドカスケード仮説を支持する.

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