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血中のモザイクY染色体喪失に対する遺伝的傾向

Deborah J Thompson1, Giulio Genovese2,3,4, Jonatan Halvardson5

  • 1Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Nature
|November 22, 2019
PubMed
まとめ

Y染色体 (LOY) のモザイク喪失は男性では一般的です. 遺伝的要因がLOYに影響し 癌の感受性やより広範な健康への影響と結びつけ ゲノム不安定性や老化に関する洞察を明らかにしています

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