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Updated: Jan 3, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

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DNP強化メチル固体NMRスペクトルによるタンパク質構造の探索

Jiafei Mao1,2, Victoria Aladin2,3,4, Xinsheng Jin5

  • 1Institute of Biophysical Chemistry , Goethe University Frankfurt , 60438 Frankfurt am Main , Germany.

Journal of the American Chemical Society
|November 23, 2019
PubMed
まとめ

この研究では,ダイナミック・ニュークレア・ポラライゼーション (DNP) 強化固体NMR (ssNMR) を使用したタンパク質構造分析のための新しいメチルベースのツールキットが導入されています. この方法は,メチル群をセンサーと"NMR トーチ"として使用して,タンパク質の包装とリガンド結合部位を明らかにします.

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