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Updated: Jan 3, 2026

Pan-myeloid Differentiation of Human Cord Blood Derived CD34+ Hematopoietic Stem and Progenitor Cells
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MLLT3はヒトの造血幹細胞の自己再生と移植を制御する

Vincenzo Calvanese1,2, Andrew T Nguyen3, Timothy J Bolan3

  • 1Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA. vincalv@gmail.com.

Nature
|November 29, 2019
PubMed
まとめ

MLLT3 (AF9) は,培養中のヒト造血幹細胞 (HSC) の維持に不可欠である. MLLT3の発現を安定させることで,移植のためのHSCの重要な拡張が可能になり,再生医療における重要な課題に取り組んでいます.

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