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Updated: Jan 3, 2026

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
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プラズモディアム・ファルシパラムのトランスポーター PfCRT の構造と耐薬性

Jonathan Kim1, Yong Zi Tan1,2, Kathryn J Wicht3

  • 1Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.

Nature
|November 29, 2019
PubMed
まとめ

プラズモディアム・ファルシパラムマラリアの薬剤耐性は大きな課題です この研究は,PfCRTトランスポーターの原子構造を明らかにし,主要な抗マラリア薬であるクロロキーンとピペラキーンに対する耐性をどのように変異させるかを説明します.

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