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Updated: Jan 2, 2026

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HBO1は白血病の幹細胞を維持するために必要です

Laura MacPherson1,2, Juliana Anokye1, Miriam M Yeung1

  • 1Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

Nature
|December 13, 2019
PubMed
まとめ

研究者は,HBO1を急性骨髄性白血病 (AML) の白血病幹細胞維持の重要なレギュラーとして特定しました. 新種の小分子でHBO1を抑制すると,患者由来AML細胞に有効性が示され,新しい治療戦略が提供されました.

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