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ガン治療のための長寿エフェクタ T 細胞を対象とした REGNASE-1 プログラム

Jun Wei1, Lingyun Long1, Wenting Zheng2

  • 1Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.

Nature
|December 13, 2019
PubMed
まとめ

REGNASE- 1をターゲットにすることで,CD8+ T細胞を長寿命のエフェクタ細胞に再プログラムし,がんの免疫療法を大幅に改善します. このアプローチはT細胞の持続性と機能を高め,臨床前モデルの治療効果を高めます.

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