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関連する概念動画

Body Planes01:06

Body Planes

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Body planes in anatomy are imaginary flat surfaces used as reference points to divide the body into sections for anatomical study. These planes are essential for understanding the orientation, relationships, and spatial organization of anatomical structures.
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
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Centroid of a Body01:16

Centroid of a Body

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The centroid is an important concept in engineering, physics, and mechanics. It is the geometric center of a body. It always lies within the body except in cases with holes or cavities. When the material that a body is composed of is uniform or homogeneous, the centroid coincides with its center of mass or the center of gravity.
For a homogeneous body with constant density, the centroid can usually be found using equations representing a balance of the moments of the body's volume. If the...
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Structural Organization of the Human Body: An Overview01:18

Structural Organization of the Human Body: An Overview

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It is convenient to consider the body's structures in terms of fundamental levels of organization that increase in complexity: subatomic particles, atoms, molecules, organelles, cells, tissues, organs, organ systems, and organisms.
To study the chemical level of organization, scientists consider the simplest building blocks of matter: subatomic particles, atoms, and molecules. All matter in the universe is composed of one or more unique pure substances called elements, familiar examples of...
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Centroid of a Body: Problem Solving01:03

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The centroid of a body is a crucial concept in engineering and physics. Finding the centroid of a body can help determine its stability, its balance point, and even its design. In this context, consider a thin wire bent in the form of a quarter circular arc. Polar coordinates are used to calculate the centroid. The wire is first divided into small differential elements of a length equal to the radius multiplied by the differential angle.
The x-coordinates and y-coordinates of each element's...
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Coordinate Plane01:21

Coordinate Plane

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The Cartesian coordinate plane is a fundamental structure in mathematics that enables the visualization of relationships between numerical values in two dimensions. It is formed by two intersecting number lines: a horizontal x-axis and a vertical y-axis. These axes meet at the origin, the point where both values are zero. Their intersection divides the plane into four quadrants labeled in a counterclockwise direction starting from the upper right.An ordered pair of numbers represents every...
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Introduction to the Skeletal System01:20

Introduction to the Skeletal System

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The skeletal system is the central framework of the body, consisting of different connective tissues: bones, cartilage, tendons, and ligaments.
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
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Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
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人体 の 共通 の 座標 枠 に 向かっ て

Jennifer E Rood1, Tim Stuart2, Shila Ghazanfar3

  • 1Klarman Cell Observatory, Broad Institute, Cambridge, MA 02142, USA.

Cell
|December 14, 2019
PubMed
まとめ

個体間の分子と細胞の組織をマッピングするために新しい計算方法が必要です. 生物学的多様性や空間的なスケールを理解するための 共通の枠組みに 多様なデータを統合することです

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科学分野:

  • ゲノミクスと分子生物学
  • コンピュータ生物学
  • バイオ情報学

背景:

  • フェノタイプの異質性は,個体間の遺伝的および分子的な違いから生じる.
  • 先進的な技術は 微細で空間的に解明された 分子プロフィールを提供します
  • 多個体の臓器データを統合することは 生物学的組織を理解するために不可欠です

研究 の 目的:

  • 生物学的データの共通の座標フレームワークを作成するための計算戦略をレビューする.
  • 複数の個人のデータを統一された参照地図に統合する課題に取り組む.
  • 空間生物学における多スケール分析方法の必要性を強調する.

主な方法:

  • データ統合と空間マッピングの既存の計算アプローチのレビュー.
  • 個体間の解剖学的変化を管理するための戦略の議論.
  • マルチスケール空間プロファイルの技術的および分析的欠陥の特定

主要な成果:

  • 現在の方法は,異質な個人データから一貫した参照マップを作成する上で課題に直面しています.
  • 共同の座標枠組を確立する上で,解剖学的変化を扱うことは重要な障害です.
  • 新しいコンピューティングツールとテクノロジーの需要は大きい.

結論:

  • 分子と細胞の組織をマッピングするには,共通の座標フレームワークを確立することが不可欠です.
  • 個人間でのデータを統合するには,高度なコンピューティングと技術的なソリューションが必要です.
  • 生物学的複雑性を捉えるために 将来の研究が多層面分析に 焦点を当てる必要があります