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Updated: Jan 1, 2026

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潰瘍性大腸炎におけるNFKBIZ経路に収束する頻繁な変異

Nobuyuki Kakiuchi1,2,3, Kenichi Yoshida1, Motoi Uchino4

  • 1Department of Pathology and Tumour Biology, Kyoto University, Kyoto, Japan.

Nature
|December 20, 2019
PubMed
まとめ

慢性的な炎症は 選択されたクローンによって 腸の改造を促します これらの突然変異は,特にNFKBIZにおいて,がんの発症に影響を与え,大腸がんにおける潜在的な治療的脆弱性を明らかにする.

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