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遺伝子プロモーターにおけるグアニン酸化とG四重複の相互作用

Aaron M Fleming1, Cynthia J Burrows1

  • 1Department of Chemistry , University of Utah , 315 South 1400 East , Salt Lake City , Utah 84112-0850 , United States.

Journal of the American Chemical Society
|December 28, 2019
PubMed
まとめ

反応性酸素種 (ROS) の遺伝子調節はDNA酸化とG四重折りによる. このプロセスは,8-オクソ-7,8-ジヒドログアニン (OG) と OGG1 を含め,ストレス反応とDNA修復遺伝子に影響を与えます.

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