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静脈内BCG予防接種後のマカクの結核予防

Patricia A Darrah1, Joseph J Zeppa2, Pauline Maiello2

  • 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.

Nature
|January 3, 2020
PubMed
まとめ

マカクにバチルス・カルメット・ゲーリン (BCG) ワクチンを静脈内投与すると,Mycobacterium tuberculosis (Mtb) 感染に対する保護が著しく強化されます. この新しい投与方法は,強固なT細胞反応を促進し,ワクチン接種対象者の検出可能なMtb感染をほぼ排除します.

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