関連する実験動画

Updated: Dec 30, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Substrate Generation for Endonucleases of CRISPR/Cas Systems

Published on: September 8, 2012

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抗CRISPRウイルスのリングヌクレアスは,CRISPR型免疫を低下させる

Januka S Athukoralage1, Stephen A McMahon1, Changyi Zhang2,3

  • 1Biomedical Sciences Research Complex, School of Biology, University of St Andrews, St Andrews, Fife, UK.

Nature
|January 17, 2020
PubMed
まとめ

ウイルスは,サイクルテトラアデニラート (cA4) 信号分子を分解する新しい酵素であるAcrIII-1を使用して,細菌のCRISPR免疫を回避することができます. この発見は CRISPR 防御システムを無効にする 新しいウイルスの戦略を明らかにしています

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