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Updated: Dec 30, 2025

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
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Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation

Published on: August 13, 2013

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VISTAは,ナイヴT細胞の静止と周辺の耐性のチェックポイントレギュラータです

Mohamed A ElTanbouly1, Yanding Zhao2,3, Elizabeth Nowak1

  • 1Department of Microbiology and Immunology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.

Science (New York, N.Y.)
|January 18, 2020
PubMed
まとめ

V型免疫グロブリン領域を含むT細胞活性化抑制剤 (VISTA) は,T細胞の静止状態を維持し,マウスの自己免疫を防ぐ. VISTAの喪失は自己反応性を高め,免疫耐性におけるその重要な役割を強調する.

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