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Updated: Apr 23, 2026

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ATP13A2の欠乏はリゾソームポリアミンの輸出を妨害する

Sarah van Veen1, Shaun Martin1, Chris Van den Haute2,3

  • 1Laboratory of Cellular Transport Systems, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.

Nature
|January 31, 2020
PubMed
まとめ

ATP13A2は,細胞の健康に不可欠なリゾソームポリアミンエクスポーターとして特定されています. パーキンソン病のような 神経退行性疾患に繋がる 機能障害により ポリアミンの輸送が妨げられ 細胞が死に至ります

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