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Updated: Dec 29, 2025

Purification of Hsp104, a Protein Disaggregase
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Purification of Hsp104, a Protein Disaggregase

Published on: September 30, 2011

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ポリペプチドループをHsp100デサグリゲーゼによって漸進的に流出させる

Mario J Avellaneda1, Kamila B Franke2, Vanda Sunderlikova1

  • 1AMOLF, Amsterdam, The Netherlands.

Nature
|January 31, 2020
PubMed
まとめ

この研究は,ClpB分解酵素がループ型ポリペプチドを処理し,タンパク質集積物からそれらを抽出できることを示しています. この発見は,細胞タンパク質の品質管理に意味を持つ,タンパク質分解と再折畳みのモデルを支持する.

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