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Updated: Dec 29, 2025

Quantifying Subcellular Ubiquitin-proteasome Activity in the Rodent Brain
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プロテアソームのストレスおよび無所不在に依存する相分離

Sayaka Yasuda1, Hikaru Tsuchiya1, Ai Kaiho1

  • 1Laboratory of Protein Metabolism, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

Nature
|February 7, 2020
PubMed
まとめ

ハイパーオスモティックストレス下では,核プロテアソームの焦点が液体-液体相分離によって形成されます. これらの構造は,誤って組み立てられたリボソームタンパク質を分解し,新しい核タンパク質分解区画を明らかにします.

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