ペプチドグライカンの基質とステレオ化学的制御 エシェリキア・コリア PBP1Bによるトランスペプチデーションによるクロスリンク

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Updated: Dec 28, 2025

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
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Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking

Published on: December 17, 2013

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Anita C Catherwood, Adrian J Lloyd, Julie A Tod

    Journal of the American Chemical Society
    |February 13, 2020
    PubMed
    まとめ

    新しいアッセイでは,ペニシリン結合タンパク質 (PBPs) が細菌の細胞壁合成においてどのように機能するか明らかにした. この研究はPBPを 抗生物質の標的ではなく 酵素として特徴付け 抗生物質のメカニズムに関する理解を深めています

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