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Updated: Dec 28, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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p53の喪失は,頭頸部がんにおけるニューロンの再プログラムを引き起こします

Moran Amit1, Hideaki Takahashi2,3, Mihnea Paul Dragomir4

  • 1Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. mamit@mdanderson.org.

Nature
|February 14, 2020
PubMed
まとめ

腫瘍に関連した感覚神経は アドレナージックになり 口腔がんの成長を促します TP53の損失と miR-34aのダウンレギュレーションによって引き起こされるこの再プログラムが潜在的な治療目標です.

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