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Updated: Dec 28, 2025

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カナビノイドCB2/Gi複合体のヌクレオチドフリー状態

Diane L Lynch1, Dow P Hurst1, Patricia H Reggio1

  • 1Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC 27412, USA.

Cell
|February 22, 2020
PubMed
まとめ

2つの新しい研究により,カンナビノイド受容体2 (CB2) がGiタンパク質に結合する冷凍EM構造が明らかになった. これらの発見はCB2とCB1の結合を区別し,Gタンパク質シグナル伝達においてヌクレオチドフリー状態を示唆する.

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