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Updated: Dec 27, 2025

Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis
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Laser Capture Microdissection of Mouse Embryonic Cartilage and Bone for Gene Expression Analysis

Published on: December 18, 2019

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脂質の存在はSOX9経由で骨格の祖先細胞の運命を決定する

Nick van Gastel1,2,3,4,5, Steve Stegen1,2, Guy Eelen6,7

  • 1Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.

Nature
|February 28, 2020
PubMed
まとめ

脂質の不足は,SOX9発現を増加させるFOXO転写因子を活性化することによって,軟骨の形成を促進します. この代謝適応は,無血管環境における骨格の原始細胞にとって極めて重要です.

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