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Updated: Dec 27, 2025

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
08:32

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

Published on: May 23, 2025

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CRISPR 適応による全ゲノムにわたる混乱は,抗生物質感受性の複雑な遺伝子を明らかにします

Wenyan Jiang1, Panos Oikonomou1, Saeed Tavazoie1

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA; Department of Systems Biology, Columbia University, New York, NY 10032, USA; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

Cell
|February 29, 2020
PubMed
まとめ

CRISPR適応媒介型ライブラリ製造 (CALM) は,細菌細胞から包括的なCRISPRiライブラリを作成し,コストを大幅に削減し,遺伝子機能の研究や抗生物質耐性メカニズムの発見に対する感度を増やす.

キーワード:
CRISPRの適応についてCRISPR ライブラリ抗生物質の強化抗生物質に対する耐性機能的ゲノミクス歴史的な偶然性

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