2007年から2018年までの米国におけるブランド医薬品のリスト価格,純価格および割引価格の変化
Inmaculada Hernandez1,2, Alvaro San-Juan-Rodriguez1,2, Chester B Good2,3,4,5
1Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania.
JAMA
|March 4, 2020
まとめ
製造者による割引は2007年から2018年にかけての ブランド医薬品のリスト価格の上昇を大幅に相殺した. リスト価格が急上昇した一方で,実質的な割引と割引により,純価格は控えめに上昇した.
科学分野:
- 健康経済学
- 医薬品の価格設定
- 薬物市場分析
背景:
- ほとんどの薬の価格調査はリスト価格に焦点を当てており,製造業者の大幅な割引や割引は無視されています.
- これらの割引は過去10年間で大幅に増加し,実際の薬のコストに影響を与えています.
研究 の 目的:
- ブランド医薬品のリスト価格,純価格,割引の変動を分析する.
- 値引きがリスト価格の上昇を相殺する程度を定量化する.
主な方法:
- 米国で販売されている602種類のブランド医薬品の2007年から2018年の価格データを遡及的に分析した.
- 純価格は,同社が報告した売上高と販売台数に基づいて推定された.
- 分析には,メディケイドと他の支払者に対する価格と割引の傾向が含まれており,利用率によって加重され,インフレに調整されています.
主要な成果:
- 2007年から2018年にかけて,リスト価格は159% (年間9.1%) 増加し,純価格は60% (年間4.5%) 増加した.
- リスト価格の上昇の62%を相殺した.
- 多発性硬化症の治療と脂質低下剤の価格上昇が顕著であった.
結論:
- ブランド医薬品のリスト価格と純価格の両方が2007年から2018年の間に大幅に上昇しました.
- 製造業者の割引は,カテゴリー価格の上昇の影響を軽減する上で重要な役割を果たしましたが,クラス間では大きな変動がありました.
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