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DELE1によって調整される経路は,ミトコンドリアのストレスをシトソールに伝達する

Evelyn Fessler1, Eva-Maria Eckl1, Sabine Schmitt2

  • 1Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany.

Nature
|March 6, 2020
PubMed
まとめ

科学者はミトコンドリアのストレスと 細胞の統合ストレス反応を 結びつける新しい経路を発見しました この経路はミトコンドリアのプロテアゼOMA1とタンパク質DELE1が関与し,細胞の恒常性にとって重要なキナーゼHRIを活性化させます.

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