関連する実験動画

Updated: Dec 27, 2025

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores
11:38

Quantifying the Binding Interactions Between CuII and Peptide Residues in the Presence and Absence of Chromophores

Published on: April 5, 2022

2.9K

タンパク質への移行金属イオン結合の熱力学

Lin Frank Song, Arkajyoti Sengupta, Kenneth M Merz

    Journal of the American Chemical Society
    |March 7, 2020
    PubMed
    まとめ

    タンパク質への移行金属 (TM) イオン結合の正確なモデリングは,生物学的プロセスを理解するために不可欠です. この研究は,プロトネーション効果を含むTMイオン結合熱力学を正確に予測する最適化されたm12-6-4電位を導入します.

    さらに関連する動画

    Thermochemical Studies of NiII and ZnII Ternary Complexes Using Ion Mobility-Mass Spectrometry16:11

    Thermochemical Studies of NiII and ZnII Ternary Complexes Using Ion Mobility-Mass Spectrometry

    Published on: June 8, 2022

    2.6K
    Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry13:26

    Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry

    Published on: September 13, 2014

    62.6K

    関連する概念動画

    The Equilibrium Binding Constant and Binding Strength02:18

    The Equilibrium Binding Constant and Binding Strength

    The equilibrium binding constant (Kb) quantifies the strength of a protein-ligand interaction. Kb can be calculated as follows when the reaction is at equilibrium:
    14.7K
    The Equilibrium Binding Constant and Binding Strength02:18

    The Equilibrium Binding Constant and Binding Strength

    9.8K
    Metal-Ligand Bonds02:51

    Metal-Ligand Bonds

    The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
    In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
    23.5K
    Crystal Field Theory - Octahedral Complexes02:58

    Crystal Field Theory - Octahedral Complexes

    Crystal Field Theory
    To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
    CFT focuses on...
    30.1K
    Complexation Equilibria: The Chelate Effect01:19

    Complexation Equilibria: The Chelate Effect

    In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
    1.0K
    Bonding in Metals02:32

    Bonding in Metals

    Metallic bonds are formed between two metal atoms. A simplified model to describe metallic bonding has been developed by Paul Drüde called the “Electron Sea Model”. 
    51.5K