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Updated: Dec 26, 2025

In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
07:25

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補足信号は,化学療法による免疫におけるB細胞の逆効果を決定する

Yiwen Lu1, Qiyi Zhao2, Jian-You Liao3

  • 1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China; Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China.

Cell
|March 7, 2020
PubMed
まとめ

化学療法により,特定のB細胞サブセット (ICOSL+) が誘発され,T細胞集団を変化させることで抗腫瘍免疫が強化されます. このB細胞サブセットのスイッチは,がん治療への反応において極めて重要です.

キーワード:
B セルサブセットICOSL について補足する免疫細胞死

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