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Methods for Detecting Cough and Airway Inflammation in Mice
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Mycobacterium tuberculosis Sulfolipid-1 ノシセプティブニューロンを活性化し,咳を誘発する

Cody R Ruhl1, Breanna L Pasko1, Haaris S Khan1

  • 1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell
|March 7, 2020
PubMed
まとめ

Mycobacterium tuberculosis (Mtb) は肺結核と咳の原因となっている. Mtbはスルフォリピド-1 (SL-1) という分子を生成し 肺の神経細胞を活性化し 咳を起こすことを発見しました この発見は この病原体が 重要な症状を誘発する 新しいメカニズムを明らかにしています

キーワード:
咳するグリコリピドホスト病原体粘膜免疫学ミコバクテリア神経免疫ノシセプターサルフォリピド結核

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