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Updated: Dec 26, 2025

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
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Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage

Published on: January 31, 2018

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RNAPIIプールの調節はDNA損傷応答に不可欠である

Ana Tufegdžić Vidaković1, Richard Mitter2, Gavin P Kelly2

  • 1Mechanisms of Transcription Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

Cell
|March 7, 2020
PubMed
まとめ

RPB1 K1268でのRNAポリメラーゼII (RNAPII) のユビキティレーションは,修復とRNAPIIの分解を含むDNA損傷反応を調整する. この調節は細胞の生存と転写回復に不可欠です.

キーワード:
DNA 損傷RNAポリメラーゼII紫外線照射トランスクリプションユビキチンどこにでもいる

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