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Updated: Dec 26, 2025

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
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生体細胞内のカルボキシル残留物における化学選択的生物結合のための2H-アジリン基反応剤

Nan Ma1, Jun Hu1, Zhi-Min Zhang1

  • 1School of Pharmacy, Jinan University, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development, Ministry of Education (MOE) of China, 601 Huangpu Avenue West, Guangzhou 510632, China.

Journal of the American Chemical Society
|March 12, 2020
PubMed
まとめ

研究者らは,選択的なタンパク質改変のための新しい化学探査機,3-フェニル-2H-アジリンを開発しました. この方法はカルボキシル基を効率的に標的にし,病気の治療と研究のための化学生物学のツールを拡張します.

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