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Updated: Dec 26, 2025

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
15:33

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation

Published on: August 13, 2013

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BTG1とBT2によるmRNAの不安定化は,T細胞の静止状態を維持する

Soo Seok Hwang1, Jaechul Lim1, Zhibin Yu1,2,3

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.

Science (New York, N.Y.)
|March 14, 2020
PubMed
まとめ

研究では,BTG1とBTG2 (BTG1/2) をT細胞静止の重要な調節体として特定した. これらのタンパク質は,メッセンジャーRNA (mRNA) のレベルを低下させ,不適切な活性化と潜在的な病気を防ぐことで,T細胞の休息状態を維持します.

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