関連する実験動画

Updated: Dec 26, 2025

Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II
10:39

Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II

Published on: February 26, 2018

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SRPK1-Catalyzed Protamine Phosphorylationのスプライシングキナーゼによる受精卵細胞における親子のゲノム再プログラミングの開始

Lan-Tao Gou1, Do-Hwan Lim1, Wubin Ma2

  • 1Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

Cell
|March 15, 2020
PubMed
まとめ

スプライシングキナーゼSRPK1は,プロタミンをリン酸化することによって受精後にプロタミンとヒストンの交換を開始する. このリン酸化は 発達初期に親のゲノム再プログラムとクロマチンの再編成に不可欠です

キーワード:
SRタンパク質特異キナーゼ授精するゲノム再プログラムヒストンチャペロンリン酸化プロタミンプロタミンとヒストンの交換シゴトの発達

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