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Updated: Dec 26, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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リシリリド生物合成における酸化炭素の骨格の再編成

Olga Tsypik1, Roman Makitrynskyy1, Britta Frensch2

  • 1Department of Pharmaceutical Biology and Biotechnology, Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Straße 19, 79104 Freiburg, Germany.

Journal of the American Chemical Society
|March 18, 2020
PubMed
まとめ

この研究では,Streptomyces bottropensisの酵素RslO5,RslO9,およびRslO8がポリケチド前駆体をどのように再配置するか明らかにしています. リシリリドやルピナシジンAのような複雑な分子を生成します

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