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Updated: Dec 26, 2025

CD Spectroscopy to Study DNA-Protein Interactions
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SWI/SNF複合体のクリオ-EM構造は,核細胞に結合している

Yan Han1, Alexis A Reyes1,2, Sara Malik1

  • 1Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.

Nature
|March 20, 2020
PubMed
まとめ

研究者は,Saccharomyces cerevisiae SWI/SNFクロマチンリモデラーを原子に近い解像度で視覚化しました. この構造は,SWI/SNFが核細胞とどのように相互作用し,DNAのアクセシビリティと遺伝子活性化を助けるかを明らかにします.

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