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Updated: Dec 25, 2025

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人間のグルカゴン受容体によるGsとGiの認識の構造的基礎

Anna Qiao1,2,3, Shuo Han1,2, Xinmei Li3,4

  • 1CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.

Science (New York, N.Y.)
|March 21, 2020
PubMed
まとめ

構造的研究により,ヒトのグルカゴン受容体 (GCGR) が異なるGタンパク質に結合する方法が明らかになった. 受容体細胞内ループの重要な違いは,GsまたはGi1タンパク質結合の選択性を決定する.

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