関連する実験動画

Updated: Dec 25, 2025

DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis
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DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis

Published on: October 6, 2017

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合成ヌクレオチドによるポリメラーゼ増幅による変異性DNA損傷のシーケンス固有の定量化

Claudia M N Aloisi1, Arman Nilforoushan1, Nathalie Ziegler1

  • 1Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, 8092 Zurich, Switzerland.

Journal of the American Chemical Society
|March 21, 2020
PubMed
まとめ

研究者は,エンジニアリングされたポリメラーゼと人工ヌクレオチドを使用して,DNAアダクト,特にO6-カルボキシメチルグアニンを検出および定量化するための新しい方法を開発しました. この画期的な発見は 化学的変異を理解し 癌のバイオマーカーを特定するのに役立ちます

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