前運動皮質のハンドノブ領域は,身体全体を構成的に表現する
Francis R Willett1, Darrel R Deo2, Donald T Avansino3
1Department of Neurosurgery, Stanford University, Stanford, CA, USA; Department of Electrical Engineering, Stanford University, Stanford, CA, USA; Howard Hughes Medical Institute at Stanford University, Stanford, CA, USA.
Cell
|March 30, 2020
まとめ
研究者達は前運動皮質の"構成"神経コードを発見し,四肢の動きを結びつけています. この発見は四肢麻痺患者の 運動制御と脳とコンピュータの インタフェースの理解を進めるものです
科学分野:
- 神経科学
- モーター コントロール
- ブレイン・コンピュータ・インターフェース
背景:
- 単一のニューロンレベルでモーターホムンクルスの組織は不明である.
- 運動皮質領域における身体部分の相互作用は十分に理解されていません.
研究 の 目的:
- 顔,頭,腕,足の動きの 神経表現を調査する 前運動皮質のハンドノブ領域.
- 四肢麻痺患者の運動制御の基礎となる 神経コードの原理を解明する.
主な方法:
- 前運動皮質 (前中枢回頭) のハンドノブ領域での多ユニット記録を使用した.
- 四肢麻痺患者の顔,頭,腕,足の動きの 神経表現を研究しました
主要な成果:
- 伝統的なモデルとは対照的に,研究されたすべての動きの強力な表現を発見しました.
- 四肢を繋ぐ部分的な 神経コードを特定した
- このコードは,四肢をコードするコンポーネントと,四肢を横断する類似の動きを表す動きをコードするコンポーネントで構成されています.
結論:
- 構成コードは,四肢間のスキルの移転を容易にする.
- 運動系が動きを構成する仕組みを 理解するための新しい枠組みを提供します
- 整体皮質内脳コンピュータインターフェースの 開発を可能にしました
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