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Updated: Dec 25, 2025

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
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Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

Published on: August 9, 2011

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カプシド の 組立 の 経路 を 決定 する 早期 の 中間 構造 の 急速 な 形成

Roi Asor1, Christopher John Schlicksup2, Zhongchao Zhao2

  • 1Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel.

Journal of the American Chemical Society
|April 3, 2020
PubMed
まとめ

B型肝炎のカプシド組は,多数の潜在的な経路をナビゲートすることによって,迅速に機能的なカプシドを形成します. この研究では 組立条件が経路を決定し タンパク質の殻形成を効率的にするために 閉じ込められた中間物質を最小限に抑えることを明らかにしました

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Viral Structure

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Disassembly of Intermediate Filaments

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The Structure of Intermediate Filaments01:19

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The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of microfilaments (7 nm) and the microtubules (25 nm).  These filaments are highly stable and can remain intact when exposed to high salt concentrations and detergents. These filaments are responsible for providing stability and mechanical support to the cells. They also help in cell adhesion and maintaining tissue integrity.
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Protein Complex Assembly

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