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Updated: Dec 25, 2025

Chromatin Isolation by RNA Purification ChIRP
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U1 snRNPは,非コーディングRNAのクロマチンの保持を調節する

Yafei Yin1, J Yuyang Lu2, Xuechun Zhang2

  • 1Tsinghua-Peking Joint Center for Life Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing, China. yafei@tsinghua.edu.cn.

Nature
|April 3, 2020
PubMed
まとめ

研究者らは,U1小核リボ核タンパク質 (snRNP) が特定のRNAモチーフに結合し,ロングノンコーディングRNA (lncRNAs) をクロマチンに誘導することを発見した. この発見は,lncRNAの局所化と機能におけるU1 snRNPの新しい役割を明らかにしています.

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