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Updated: Dec 24, 2025

Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells
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保存 さ れ た 樹突 細胞 調節 プログラム は,抗腫瘍 免疫 を 制限 する

Barbara Maier1,2,3, Andrew M Leader1,2,3, Steven T Chen1,2,3

  • 1The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Nature
|April 10, 2020
PubMed
まとめ

研究 者 たち は,抗がん 免疫 療法 を 阻害 する 新しい 型 の 樹状 細胞 (DC) を 特定 し まし た. これらの成熟した免疫調節分子 (mregDCs) の特定のシグナル伝達経路を遮断することで,抗腫瘍免疫が回復し,腫瘍の成長が減少しました.

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