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Updated: Dec 23, 2025

Visualization of G3BP Stress Granules Dynamics in Live Primary Cells
10:12

Visualization of G3BP Stress Granules Dynamics in Live Primary Cells

Published on: May 21, 2014

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凝縮によるG3BP駆動ストレスの粒子の結合によるRNA誘発型切り替えとクラスタリング

Jordina Guillén-Boixet1, Andrii Kopach2, Alex S Holehouse3

  • 1Center for Molecular and Cellular Bioengineering, Biotechnology Center, Technische Universität Dresden, Tatzberg 47/49, 01307 Dresden, Germany.

Cell
|April 18, 2020
PubMed
まとめ

細胞はストレス中にストレス粒 (SGs) を形成する. この研究は,mRNAの相互作用によって,G3BPタンパク質がどのように構成変化し,これらの重要なストレス粒子を組み立てるかを明らかにしています.

キーワード:
G3BP神経変性疾患RNPの粒液体から固体への移行段階分離ストレス・グランブルストレス反応

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4D Imaging of Protein Aggregation in Live Cells

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