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Updated: Dec 23, 2025

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae
10:57

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae

Published on: February 16, 2015

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Hrd1ユビキチンリガゼ複合体によるER関連タンパク質分解の構造的基礎

Xudong Wu1, Marc Siggel2, Sergey Ovchinnikov3

  • 1Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|April 25, 2020
PubMed
まとめ

研究者らは,エンドプラズマ網膜関連分解 (ERAD-L) に不可欠なHrd1複合体の構造を明らかにした. この発見は タンパク質分解の重要なステップである 逆転移のメカニズムを明らかにします

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Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae

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Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta

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